Promoters maintain their relative activity levels under different growth conditions

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Promoters maintain their relative activity levels under different growth conditions

Most genes change expression levels across conditions, but it is unclear which of these changes represents specific regulation and what determines their quantitative degree. Here, we accurately measured activities of ~900 S. cerevisiae and ~1800 E. coli promoters using fluorescent reporters. We show that in both organisms 60-90% of promoters change their expression between conditions by a const...

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ژورنال

عنوان ژورنال: Molecular Systems Biology

سال: 2013

ISSN: 1744-4292,1744-4292

DOI: 10.1038/msb.2013.59